Biotin and derivatives
Medchemexpress LLC Biotin-Gastrin Releasing Peptide, human TFA | 3085.67 | 5 MG
Biotin-Gastrin Releasing Peptide, human TFA, is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide known for its growth-stimulatory and tumorigenic properties. This product is intended for research use only and is not sold to patients.
- Biotinylated gastrin releasing peptide (GRP)
- Has growth-stimulatory and tumorigenic properties
- Intended for research use only
Medchemexpress LLC Biotin-ATRA-conjugate | 2226143-93-5 | 98.4% | C36H55N3O4S | 10MG
ATRA-biotin (biotin-ATRA-conjugate) is a biotin-labeled derivative of all-trans retinoic acid used as a tracer and affinity reagent to track ATRA distribution and interactions in biological samples. It supports biotin-streptavidin workflows and is supplied at high purity for research use only.
- Biotin tag enables streptavidin-based detection.
- Suitable for localization studies in cells and tissues.
- Compatible with pull-down and affinity capture assays.
- High purity for reproducible experimental results.
- Available in multiple laboratory-friendly pack sizes.
Biotium Dyes For Labeling Carbonyls and Carbohydrates Fluorescence Microscopy Cell and Organelle Stains Cell Surface and Membrane Dyes 1/EA
Label live cell surface glycoproteins with biotin for fixable plasma membrane staining or protein extraction GlycoLiner uses novel reactive chemistry for faster more efficient and gentler labeling compared to conventional methods Label 100 wells (200 uL) or two T75 flasks (10 mL)
Medchemexpress LLC Biotin-TEG-ATFBA | 1264662-85-2 | C27H37F4N7O6S | 25 MG
Biotin-TEG-ATFBA is a click chemistry reagent that incorporates a perfluorophenylazide group. This reagent forms a highly stable azene intermediate which undergoes insertion and addition reactions (non-intermolecular rearrangement) in moderate to good yields after photolysis. It also has an azide group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. Additionally, it can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It is intended for research use only.
- Contains a perfluorophenylazide group
- Forms a highly stable azene intermediate upon photolysis
- Undergoes insertion and addition reactions
- Features an azide group for CuAAc with alkyne-containing molecules
- Can undergo SPAAC with DBCO or BCN groups
Medchemexpress LLC M-PEG14-NHS ester | 773.86 | 50 MG
m-PEG14-NHS ester is a chemical compound commonly used in laboratory research and the manufacture of various substances. This product is supplied as a solid and exhibits chemical stability when stored under recommended conditions.
- Used in laboratory research
- Suitable for the manufacture of substances
- Supplied as a solid
- Chemically stable under recommended storage conditions
Medchemexpress LLC Biotin-LC-LC-NHS | 89889-52-1 | 98.0% | 567.7 g/mol | C26H41N5O7S | 50 MG
Biotin-LC-LC-NHS is a long-chain N-hydroxysuccinimide (NHS) activated biotinylation reagent used to label proteins, antibodies, and small molecules. The LC-LC spacer reduces steric hindrance during conjugation, and the NHS ester reacts with primary amines to form stable amide bonds.
- Provides long-chain spacer (LC-LC) to reduce steric hindrance.
- Reactive NHS ester for amine-selective conjugation.
- Suitable for labeling antibodies and small molecules.
- Solid, white to light yellow appearance; store under inert gas and protect from light.
- Soluble in DMSO; follow recommended solvent and storage guidance.
Medchemexpress LLC Bis-PEG9-NHS ester 500mg | 1008402-79-6 | 708.71 | C30H48N2O17 | 500 MG
Bis-PEG9-NHS ester is a PEG9-based bifunctional linker bearing two N-hydroxysuccinimide (NHS) ester groups, designed for amine-targeted bioconjugation and linker applications such as PROTAC and ADC synthesis. It provides a hydrophilic spacer to improve solubility and reduce aggregation during conjugation.
- Bifunctional amine-reactive crosslinker with two NHS ester groups.
- PEG9 spacer increases hydrophilicity and solubility in aqueous media.
- Suitable for PROTAC, ADC, and general bioconjugation to primary amines.
- High chemical purity (≥98%) for reliable conjugation performance.
- Viscous, colorless to light yellow material; moisture sensitive - store sealed and protected from moisture.
- Molecular weight ≈ 708.71 g/mol; molecular formula C30H48N2O17.
eMolecules Mal-PEG11-alcohol | Broadpharm |581.656 | C26H47NO13 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O | 1g | 599128887
Mal-PEG11-alcohol | Broadpharm |581.656 | C26H47NO13 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O | 1g | 599128887
Medchemexpress LLC Nsp-dmae-nhs | 194357-64-7 | 99.5% | 1 MG
NSP-DMAE-NHS is an acridinium ester chemiluminescence reagent containing an N-sulfopropyl group. It is useful in the clinical diagnostics industry, especially in automated immunochemistry analyzers. The product is for research use only and not sold to patients.
- Acridinium ester chemiluminescence reagent
- Contains n-sulfopropyl group
- Useful in the clinical diagnostics industry
- Applicable in automated immunochemistry analyzers
Medchemexpress LLC AF647-NHS ester triTEA | 407627-61-6 | 99.7% | 1259.66 | 50 MG
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647). It features an excitation wavelength (λex) of 635 nm for conventional fluorescence detection and 620 nm for instantaneous detection. This compound's NHS ester group enables covalent binding to molecules containing amino groups, such as proteins and antibodies.
- Fluorescent properties suitable for various detection methods.
- Reactive NHS ester group for covalent attachment to amino groups.
- Enables labeling of proteins, antibodies, and other biomolecules.
- Excitation at 635 nm (conventional) and 620 nm (instantaneous).
- Available in multiple quantities for research needs.
Medchemexpress LLC Biotinamidocaproyl hydrazide | 109276-34-8 | MFCD00077659 | 99.8% | 371.50 g/mol | C16H29N5O3S | 10 MG
Biotin LC hydrazide is a long-chain biotinylation reagent used to derivatize periodate-oxidized carbohydrates on glycoproteins and other biomolecules. The hydrazide moiety reacts with aldehydes generated by mild oxidation to form stable hydrazone linkages, while the long-chain spacer arm improves accessibility for detection and affinity capture. Intended for research use only.
- Reacts with periodate-oxidized carbohydrates and glycoproteins.
- Introduces a biotin tag via hydrazide chemistry for avidin/streptavidin detection.
- Long-chain spacer reduces steric hindrance and improves binding accessibility.
- Suitable for labeling, detection, and affinity purification workflows.
- Provided as a stable white solid for easy handling and storage.
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine N-hydroxysuccinimide ester | 1383932-86-2 | MFCD29267127 | 95.0% | 945.21 g/mol | C49H89N2O13P | 25 MG
DSPE-NHS is an NHS-activated phospholipid (1,2-distearoyl-sn-glycero-3-phosphoethanolamine N-hydroxysuccinimide ester) used to introduce a reactive NHS ester at liposome or nanoparticle surfaces for covalent conjugation to primary amines on proteins, peptides, and other amine-containing molecules. It self-assembles into lipid bilayers and is commonly used for antibody labeling, liposome functionalization, and nanoparticle surface modification in research applications.
- Reactive NHS ester for efficient amine coupling.
- Self-assembles into lipid bilayers for membrane incorporation.
- Enables stable amide bond formation with proteins and peptides.
- Suitable for liposome and nanoparticle surface modification.
- Available in multiple laboratory-scale package sizes for research use.
Medchemexpress LLC Bis-SS-C3-NHS ester | 98604-88-7 | 98.0% | 432.47 g/mol | C16H20N2O8S2 | 100 MG
Bis-SS-C3-NHS ester is a cleavable antibody-drug conjugate (ADC) linker containing a disulfide-based spacer and N-hydroxysuccinimide (NHS) ester reactive groups for amine coupling. It is used to attach cytotoxic payloads to antibodies and enable controlled payload release inside target cells.
- Molecular formula: C16H20N2O8S2.
- Molecular weight: 432.47 g/mol.
- Cas number: 98604-88-7.
- Purity: 98.0%.
- Appearance: white to off-white solid.
- Storage: in solvent, -80°C for up to 6 months; -20°C for up to 1 month; store sealed and away from moisture.
- Available in multiple sizes, including 100 mg, for research use.
Medchemexpress LLC Butanoic acid NHS ester (BHQ-1) | 916753-61-2 | 95.4% | 601.61 g/mol | C30H31N7O7 | 10 MG
BHQ-1 NHS is an N-hydroxysuccinimide (NHS) ester derivative of a non-fluorescent quencher designed for covalent coupling to primary amines on nucleotides, oligonucleotides, and other biomolecules. It is intended for use as a quencher in fluorescence probe and assay design and for direct labeling of fluorescently labeled nucleotides. For research use only.
- Reactive NHS ester for stable amide bond formation with amines.
- Non-fluorescent quenching suitable for fluorescence-based assays.
- High purity, typically 95.44% as stated on the COA.
- Soluble in DMSO at approximately 4.35 mg/mL; ultrasonic agitation recommended.
- Provided in milligram quantities for small-scale labeling workflows.
Medchemexpress LLC Biotin-PEG3-acid 1g | 252881-76-8 | 447.55 | C19H33N3O7S | 1 G
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker used to introduce a biotin tag with a short PEG3 spacer in PROTAC synthesis and bioconjugation workflows. The material is supplied as a 1 g purified solid (typical purity 98.0%) with molecular weight 447.55 g/mol and chemical formula C19H33N3O7S, and is accompanied by a batch-specific certificate of analysis.
- Provides a biotin handle separated by a PEG3 spacer to reduce steric hindrance
- Designed for incorporation into PROTACs and other bioconjugates
- Improves aqueous solubility compared with direct biotinylation
- Typically supplied with batch certificate showing ~98.0% purity
- Solid form with known molecular weight and formula for formulation planning